Ozempic Face: What It Is, Why It Happens, and How to Prevent It

“Ozempic face” is a term that went viral on social media to describe facial changes associated with rapid weight loss, particularly in people using Ozempic (semaglutide) or similar GLP-1 medications. While it’s not a medical diagnosis, the phrase reflects a real and noticeable effect for some individuals:
✔️ Loss of facial fat (volume)
✔️ Loose or sagging skin
✔️ A more tired or aged appearance

These features can occur with any rapid weight loss — not just Ozempic — but the speed and effectiveness of GLP-1 therapy means many people notice these changes within months.

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